On May 13, 2000, Alex Browning (Devon Sawa), a senior high school student, boards Volée Airlines Flight 180 with his fellow classmates and teachers for their senior trip to Paris. Before the plane ascends, Alex has a premonition that the flight will explode on take off, killing everyone on board. As events from his vision express themselves in reality, he panics and attempts to stop the flight. Th
e resulting commotion leads to the removal of some passengers, including Alex, orphan Clear Rivers (Ali Larter), Alex' best friend Tod Waggner (Chad E. Donella), teacher Valerie Lewton (Kristen Cloke), Alex' rival Carter Horton (Kerr Smith), Carter's girlfriend Terry Chaney (Amanda Detmer) and student Billy Hitchcock (Seann William Scott). After they are exited from the plane, none of the passengers believe Alex' statement until the airliner explodes in mid-air. The survivors are devastated, and are investigated by two FBI agents (Daniel Roebuck and Roger Guenveur Smith) who are particularly interested with Alex' vision. After attending a memorial for the Flight 180 victims, Tod accidentally hangs himself within his clothesline and is deemed as a su***de. When Alex and Clear locate his body, mortician William Bludworth (Tony Todd) tells them that Death is reclaiming the lives of those who escaped its original plan, as proven after Terry is hit by a speeding bus. Whilst watching a newsfeed detailing Flight 180's aftermath, Alex concludes that Death is killing the survivors in accordance with the sequence of their intended demises on the plane. Lewton from a kitchen knife impalement which ultimately causes a house explosion. The remaining survivors (Alex, Clear, Carter, and Billy) are reunited as Alex explains the situation. Frustrated by Terry's loss and no control over his life, Carter attempts su***de by stalling his car along railroad tracks. Though he changes his mind, Alex rescues him by ripping his seatbelt before the train collides his car. Billy is unexpectedly decapitated by a shrapnel from the wreckage.